Bicarbonate therapy in severe metabolic acidosis pdf

It has been suggested that this article be merged with Hypokalemic acidosis. Metabolic acidosis is a condition that occurs when the body produces excessive quantities of acid bicarbonate therapy in severe metabolic acidosis pdf when the kidneys are not removing enough acid from the body.

If unchecked, metabolic acidosis leads to acidemia, i. Its causes are diverse, and its consequences can be serious, including coma and death.

Together with respiratory acidosis, it is one of the two general causes of acidemia. Acidosis refers to a process that causes a low pH in blood and tissues.

Acidemia refers specifically to a low pH in the blood. In most cases, acidosis occurs first for reasons explained below. Free hydrogen ions then diffuse into the blood, lowering the pH.