Medications
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Clomipramine

Trade name: Anafranil, Anafranil SR Pharmacological Properties Clomipramine is one of the key representatives of tricyclic antidepressants, alongside amitriptyline and imipramine. In terms of its pharmacological profile, it occupies an intermediate position between the two: amitriptyline primarily exerts a sedative effect, imipramine — a stimulating one, while clomipramine combines both effects in...
Medications
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Mianserin

Trade name: Miansec, Lerivon, Deprexolet, Miansegen Mechanism of Action: Focus on Neurotransmitter Regulation Mianserin is a tetracyclic antidepressant with a unique mechanism of action and pronounced sedative properties. It is often compared to mirtazapine, as both drugs act on alpha-2 adrenergic receptors. However, there are significant biochemical and clinical differences between them....
Medications
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Vortioxetine

Trade Names: Brintellix Vortioxetine: How Does This Antidepressant Work and What to Expect? If you’ve been prescribed vortioxetine, you’re probably wondering what it is and how it might help. This is a next-generation antidepressant with a unique twist: it doesn’t just tweak serotonin levels—it also fine-tunes how your brain communicates across multiple...
Medications
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Trazodone

Trade Names: Trazodone Neuraxpharm, Trittico CR, Trittico XR Trazodone: What Is This Drug and How Does It Work? Trazodone is an antidepressant with a fascinating history and a wide range of uses. It’s often prescribed not just for depression, but also for insomnia, anxiety, and even certain potency issues. However, this drug...
Disorders
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Anxiety-Depressive Disorder

Anxiety-Depressive Disorder: Understanding Interconnections and Symptoms In anxiety-depressive disorder (ICD-10 — code F41.2, ICD-11 — code 6A73), symptoms of both anxiety and depression are present simultaneously, but neither reaches the quantitative threshold necessary for an independent diagnosis. This condition is considered subpsychotic, situated between psychotic and neurotic disorders. The symptoms can...
Disorders
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Generalized Anxiety Disorder

Constant Anxiety: When the Mind Knows No Peace Generalized anxiety disorder (GAD) is a condition in which anxiety becomes a constant companion in life. Imagine a person who wakes up every day with the thought: “What if something goes wrong?” And even if there are no problems in life, this person...